Here , the authors study the associations between the gut microbiota and immunotherapy response and irAE development using a clinically homogenous trial cohort of patients in Australia and the Netherlands who presented with melanoma treated with neoadjuvant combination ICIs.
A highly homogeneous prospective clinical trial cohort was utilized to show that a gut microbiome associated with higher fiber and #omega3 consumption is beneficial to facilitating optimal anti-tumor immune responses and minimizing the risk of irAEs during #immunotherapy
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